Methodology book

“Theoretical principles of heart cycle phase analysis” 
ISBN 978-3-937909-57-8

This book gives a description of the theory of the heart cycle phase analysis based on a new fundamental scientific discovery explaining the phenomena of blood flow in large blood vessels.

Previously, the concept explained the blood flow as a flow under laminar flow conditions. That was the basis for the former theories of functioning of the heart and the blood vessels. That approach was not capable of explaining many matters of the fact and conflicted with the reality. The use of improper concepts and improper conclusions made it impossible to apply any metrological basis to widely used diagnostics methods. First of all, it referred to the ECG-based diagnostics. As a consequence, all existing methods of non-invasive diagnostics of the heart and blood vessels could be considered to be rather indicating but not measuring systems.
The theory of the superfluidity of blood developed by us makes it possible to create absolutely new diagnostics criteria supported successfully with metrology, based on the relevant ECG and rheogram. The method of the phase analysis described in this book shall be treated as the first step towards the theory of the differential diagnosis of the functioning of the heart and the blood vessels. This alone would show the possibilities of a more precise determination of the cause of pathology as early as possible.
Up to present time, all methods have been based only on integral indices that allowed to diagnosticate deceases postfactum. The theory presented in this book makes it possible to forecast eventual development of pathological processes, if any, that was not the case before.
We would like to express our hope that our researches might contribute to further development of the theory of cardiology, and practicing physicians would be given a new possibility to control diseases of the cardiovascular system in a great variety of their manifestations.
 
Contents
Introduction
Part I. Theory of hemodynamics and metrological support principles when measuring cardiovascular system phase parameters
1. State of electrocardiosignals research methodology
1.1. Conceptual issues of medicobiologic signals research methodology
1.2. Current methods for cardiovascular system investigation
1.3. Paradigm of hemodynamic parameters measurement in cardiology
1.4. Prospects of hemodynamics research based on electrocardiosignals
2. Methodology for electrocardiosignals research based on graphic mathematical differentiation 
2.1. Evaluation of medicobiological signals distortion during recording
2.2. About blood vessel sanguimotion conditions
2.3. Mathematical methods for determination of minute, stroke and phase volumes based on duration of cardiac cycle
2.4. Theorem of identification of cardiac cycle phase transition parameters
2.5. ECG phases representing the myocardium electric biopotential correlation with heart geometric shape variation
2.6. Delimitation of phases using the curve of first-order derivative for ECG when conducting mathematical differentiation
3. Criteria of hemodynamic parameters indirect measurement error evaluation using the elaborated method 
3.1. General state of metrological support of indirect methods for hemodynamic parameters measurement
3.2. Sources of cardiac cycle phase transition parameters measurement errors occurring during ECG recording
3.3. Estimation of hemodynamic parameter measurement errors using the elaborated method
4. ECG recording using Cardiocode-1. Criteria of phases registered on first-order derivative curve in automatic mode
4.1. Making the patient ready for ECG recording
4.2. Setting the electrodes for ECG recording. Distinguishing features of single-channel ECG trace recorded using Cardiocode as compared with standard multi-channel ECG trace
4.3. Near-ideal ECG trace
4.4. Determination of phases based on ECG trace first-order derivative
5. Clinical practice of dynamics investigation on basis of ECG mathematical graphical differentiation
5.1. Volumetric parameters of hemodynamics measured by instruments
5.2. Investigation of boundaries of physiological norm of cardiovascular system hemodynamics. Self-regulation of normal values of hemodynamic parameters
5.3. Research of cardiovascular system parameters with pathology in some cardiac cycle phases
5.4. Orthostatic test
6. ECG and rheogram recording using Cardiocode-2
6.1. Electrodes arrangement procedure
6.2. Rheogram phase characteristic
7. Diagnostics through synchronous recording of ECG trace and rheogram
7.1. ECG and rheogram interrelations used for diagnostics purposes
7.2. Cardiovascular system functions which can be assessed using Cardiocode-2
8. Updating of cardiovascular system pathologic behavior theory based on cardiac cycle phases analysis data
8.1. Common initial conditions for pathology progress. Malfunction of intermembrane transport of biochemical elements
8.2. Thrombosis development
Part II. Atlas for functional diagnostics based on cardiac cycle analysis (ECG trace + rheogram)
9. Practical diagnostics
9.1. Relatively normal functioning of cardiovascular system
9.2. Comparison analysis of diagnostics data: heart cycle phase analysis method data against classical multi-channel ECG registration data
9.3. Comparative analysis of cardiovascular system diagnostics against background of lung diseases
10. Some special cases from practice
10.1. Phase analysis data obtained during pre-stroke & stroke periods and resuscitation & after-therapy periods
10.2. Another case of phase analysis data: stroke successfully avoided
10.3. Data of phase analysis of patient with implanted heart pacemaker
10.4. Data of phase analysis of patients with implanted artificial aortic valve and artificial ascending aorta
11. Phytotherapy of heart diseases
11.1. Case of cardiac abnormalities: weak function of heart muscle, manifestations of cardiac insufficiency
11.2. Herbal medicines recommended against heartbeats attacks
11.3. Herbal medicines used to eliminate edema caused by cardiac insufficiency
11.4. Traditional phytotherapy medicines used for relieving pains in heart area under angina pectoris
11.5. Recommendations: how to prevent angina pectoris attacks
11.6. Herbal teas in therapy of arrhythmia
11.7. Phytotherapy against heartbeats accompanied by edema
11.8. Under heartbeats induced by nervous system
11.9. Under heartbeats accompanied by insomnia
11.10. Under tachycardia
11.11. Under post-infarction conditions
11.12. Under microinfarctation
11.13. Under coronary insufficiency (CHD)
11.14. Under heart arrhythmia
11.15. Under extrasystole accompanied by hypotension
11.16. Persons suffering from coronary heart disease (CHD) with normal arterial pressure
11.17. General recommendations for diet management under any cardiac diseases
Conclusion
Bibliography